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Saquon Barkley of the New York Giants carries the ball during warmups of a preseason game against the Cincinnati Bengals, and we offer our top rushing props predictions for Week 10 based on the best NFL odds.
Saquon Barkley of the New York Giants carries the ball during warmups of a preseason game against the Cincinnati Bengals. Photo by Sarah Stier/Getty Images via AFP.

In Week 10, running backs have multiple advantageous matchups to exploit. Below are our top NFL rushing prop predictions sourced from the leading NFL prop betting sites.

In Week 9, Rhamondre Stevenson of the New England Patriots achieved over 60 rushing yards for the first time this season, totaling 87 yards on nine carries. Now, we are evaluating if he can continue his strong performance with a favorable matchup against the Indianapolis Colts in the upcoming week.

With starting quarterback Daniel Jones sidelined with a knee injury, the New York Giants are set to rely heavily on running back Saquon Barkley. Barkley is expected to carry a significant workload as the team’s primary offensive weapon in the upcoming week. Backup QB Tommy DeVito is likely to play it safe in the passing game, making Barkley even more crucial to the team’s success. The Giants’ game plan will center around Barkley’s abilities, highlighting his role as a workhorse in Jones’ absence and underscoring his importance in the offensive strategy for the week.

Tampa Bay Buccaneers running back Rachaad White is determined to achieve consecutive games with over 50 yards rushing for the first time in 2026.

In addition to our NFL Week 10 predictions and best bets, we are sharing our top NFL rushing player prop predictions for Week 10, with odds from our recommended NFL betting sites. Confidence levels are rated on a scale of 1 to 5 stars.

Week 10 NFL rushing prop predictions

  • Rhamondre Stevenson is predicted to rush for over 46.5 yards, with a -114 odds on FanDuel. This bet is rated four stars.
  • Saquon Barkley is expected to have more than 16.5 rushing attempts at -105 odds on DraftKings, receiving a four-star rating.
  • Rachaad White to rush for under 50.5 yards (-110 odds on bet365) ⭐⭐⭐⭐

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Rushing player props

Rhamondre Stevenson is predicted to have over 46.5 rushing yards, earning a four-star rating with -114 odds on FanDuel.

Stevenson’s biggest challenge this season has been playing on a struggling football team. Due to unfavorable game scripts, he has only received 10 or fewer carries in each of his last five games.

But this week, we anticipate Stevenson will receive more chances to run against a defense that gives up 125.6 rushing yards per game. The Indianapolis Colts hadn’t won a game by more than one score since Week 2 until last week.

In a tightly contested game, the Patriots’ strategy should focus on feeding Stevenson the ball and minimizing Mac Jones’ workload.

Our NFL prop betting sites have Stevenson’s total set at 47.5, with the exception of FanDuel. Given Stevenson’s impressive performance this season, every yard is crucial. Therefore, we will opt for the lower number at FanDuel, even if it means accepting a less favorable price.

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Saquon Barkley has more than 16.5 rushing attempts at -105 odds on DraftKings. ⭐⭐⭐⭐

Barkley has rushed the ball a minimum of 16 times in five out of six games this season. In the game two weeks ago, where Tommy DeVito had to step in for most of the game, Barkley ended with 36 rushing attempts.

DeVito will be back in action on Sunday, but facing the Dallas Cowboys spells trouble for him from the get-go. Hindered by a weak offensive line, his passing game will likely suffer. As a result, the Giants will heavily rely on Barkley to carry the load. Despite the Cowboys likely stacking the box, Barkley is projected to receive more than 16 carries in the game.

At present, only three out of our top five sports betting sites are providing this prop bet. DraftKings is currently offering the most competitive price, with both BetMGM and bet365 listing Barkley’s Over at -110.

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Rachaad White rushing yards under 50.5 (-110 on bet365) ⭐⭐⭐⭐

White rushed for 73 yards on 20 carries last week, making it the second game in a row where he averaged more than 3.5 yards per carry. Despite this, we are unsure if he will reach 50 yards in consecutive games for the first time this season.

White has surpassed 50 yards in a game only three times this year, with the Buccaneers winning by double digits in two of those games. The Titans are giving up an average of 114.8 rushing yards per game and 4.1 yards per carry. However, it is unlikely that the Buccaneers will dominate this game as they have in the past when White has had success.

Currently, four top sportsbooks have White’s total set at 50.5. DraftKings, bet365, and BetMGM all offer the Under at -110, while Caesars has it at -119. FanDuel sets the total at 46.5, which aligns more with our expectations. However, we recommend caution when betting on this number unless you consider taking the Over and attempting to middle.

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Picks for rushing props were made on November 10, 2026 at 8:51 a.m. ET.

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