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South Carolina Gamecocks' Zachary Davis and Arkansa Razorbacks' Tramon Mark reach for a rebound in the first half as as we make our Oregons vs. South Carolina March Madness prediction.
Zachary Davis #12 of the South Carolina Gamecocks and Tramon Mark #12 of the Arkansa Razorbacks reach for a rebound in the first half during the second round of the SEC Basketball Tournament at Bridgestone Arena on March 14, 2024 in Nashville, Tennessee. Photo by Andy Lyons of Getty Images

The Oregon Ducks, ranked No. 11, will face off against the No. 6 South Carolina Gamecocks in a highly anticipated first round match-up of the NCAA Tournament. Our top prediction for the Oregon vs. South Carolina game is based on the most favorable March Madness odds available.

The Oregon Ducks faced challenges in three of their last five regular-season games, causing doubts about their chances in March Madness. Despite this, they exceeded expectations by winning three games in a row, securing the Pac-12 Tournament championship.

The Ducks have made it to the Sweet 16 in their past four NCAA Tournament appearances and are looking to build on their previous March Madness success.

At the same time, the South Carolina Gamecocks have tied a school record for most wins in a season with 26, a milestone previously reached in 2017 when they made it to the Final Four. It is worth mentioning that three of their recent wins were against teams that are also competing in the NCAA Tournament.

Here are our top predictions and college basketball picks for the Oregon vs. South Carolina matchup in March Madness. Our confidence in these picks is rated on a 1-to-5-star scale, with odds provided by our recommended March Madness betting sites.

The odds for the Oregon versus South Carolina game are being calculated.

Prediction for the Midwest Region matchup between Oregon (No. 11) and South Carolina (No. 6)

N’Faly Dante falls short of 8.5 rebounds with a 4-star rating.

The most favorable odds are -120 on DraftKings.

We are fascinated by the unconventional style of this play, as Dante has consistently secured nine or more rebounds in seven out of the last nine games, with five of those in the last six. Nevertheless, South Carolina is known for their slow tempo, ranking among the top 10 slowest teams in the country, and they are 15th in average possession length on offense.

The Gamecocks have only had one game this season with 68 possessions, requiring an additional overtime period. As a result, Dante is likely to have fewer chances to secure rebounds compared to the faster-paced games against Arizona and Colorado.

South Carolina is excelling in rebounding, with a top-56 offensive rebounding rate of 33.1% and the third-best defensive rebounding rate in SEC play. This performance earns them a four-star rating.

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The best odds for the Oregon vs. South Carolina match-up.

DraftKings (-120)

DraftKingsFanDuelBetMGMCaesarsbet365
Under 8.5 reboundsUnder 8.5 reboundsUnder 8.5 reboundsUnder 8.5 reboundsUnder 8.5 rebounds
-120-132N/AN/A-130

At this time, only three of our top sports betting sites are offering player props for this matchup. The most favorable odds are found at DraftKings, where a $10 wager at -120 odds would result in a payout of $18.33. In comparison, the same winning bet at bet365 would pay out $17.69 at -130 odds. The -120 odds at DraftKings imply a probability of 54.55%.

In contrast to FanDuel and DraftKings, bet365 provides special “player prop milestones” that allow bettors to receive enhanced odds for players like Dante to exceed the projected total in categories such as rebounds, making it a unique feature of the platform.

Analysis of the spread and Over/Under for the Oregon vs. South Carolina game.

With the exception of DraftKings, our top sports betting sites are favoring South Carolina by 1.5 points. DraftKings and bet365 have been fluctuating between -1 and -1.5, while Caesars has seen a significant shift from a pick’em to South Carolina -1.5. The Ducks are currently a popular underdog, with 71% of early bets placed on them.

The majority of our top sports betting sites have an over/under of 132.5, but FanDuel stands out with a total of 133.5. BetMGM also had a total of 133.5, but the line was driven down by those betting on the under.

The total has more balanced action compared to the point spread, with a slight 55/45 split in favor of the Over.

Information on the Oregon vs. South Carolina game

  • When: Thursday, March 21
  • Game start: 4:00 p.m. Eastern Time
  • Location: PPG Paints Arena in Pittsburgh, Pennsylvania.
  • How to watch: TNT

Prediction for the Oregon-South Carolina game was made on Monday at 1:39 p.m. ET.

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