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Paige Bueckers #5 of the Connecticut Huskies yells after a play as we offer our best UConn vs. Iowa prediction and pick for the women's Final Four on Friday.
Paige Bueckers #5 of the Connecticut Huskies yells after a play during the first half against the USC Trojans in the Elite 8 round of the NCAA Women’s Basketball Tournament at Moda Center on April 01, 2024 in Portland, Oregon. Photo by Steph Chambers/Getty Images via AFP.

Caitlin Clark will be leading the Iowa Hawkeyes against Paige Bueckers and the UConn Huskies in the women’s Final Four of the 2024 NCAA Tournament. Our expert pick and prediction for the UConn vs. Iowa matchup are based on the most favorable Final Four odds available.

It is challenging to create a more exciting Final Four showdown than the upcoming game between Caitlin Clark’s No. 1 Iowa Hawkeyes (33-4) and Paige Bueckers’ No. 3 UConn Huskies (33-5). This highly anticipated matchup is expected to be one of the standout games of March Madness and the entire college basketball season.

A major storyline of the game is Iowa’s standout scorer, Caitlin Clark, who we analyze in depth with our top player props for the Final Four. With Clark leading the way, Iowa is favored by 2.5 points at our recommended sports betting sites. The game is scheduled to start at 9:30 p.m. ET on ESPN at Rocket Mortgage FieldHouse in Cleveland, Ohio.

Don’t underestimate Bueckers, who has once again proven herself as one of the top players in women’s basketball with an impressive tournament performance. Alongside Clark, she will be striving to secure a win on Friday in order to potentially face off against the undefeated South Carolina, the current favorite to win the championship according to the latest women’s March Madness odds.

Here is our expert prediction and pick for the UConn vs. Iowa game, in addition to our prediction for the NC State vs. South Carolina game. Odds are from our top March Madness betting sites, and confidence in the pick is rated on a scale of 1 to 5 stars.

Game information for UConn (3) vs. Iowa (1)

  • When: Friday, April 5
  • Tip-off: 9:30 p.m. ET
  • Location: Rocket Mortgage FieldHouse, situated in Cleveland, Ohio.
  • How to watch: ESPN
  • Top pick: Iowa is favored by 2.5 points with -115 odds at BetMGM.

UConn vs. Iowa odds

TeamsMoneylineSpreadTotal
Iowa-150-2.5 (-115)Over: 162.5
UConn+125+2.5 (-105)Under: 162.5

UConn vs. Iowa prediction

Iowa -2.5 ⭐⭐⭐⭐

Top odds: -115 at BetMGM

Since Iowa defeated South Carolina in last year’s Final Four, it has seemed highly likely that the two teams would face off again in this year’s NCAA Tournament. I have doubts about whether UConn has what it takes to prevent that anticipated rematch.

While Bueckers has been impressive in this tournament, Clark has been dominating March Madness all on her own. She continues to elevate her game each round, as shown by her 41 points and 12 assists to lead the Hawkeyes past defending champion LSU in the Elite Eight.

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The Tigers guard Hailey Van Lith, who was tasked with defending Clark, was left shrugging her shoulders in a meme-worthy manner after the performance of the best shooter in women’s hoops. I doubt that UConn’s defense, while effective on a per-possession basis, has the ability to contain Clark when she reaches her peak performance. Can anyone stop her when she goes full Super Saiyan?

I delve deeper into the superstar in my article on betting Caitlin Clark player props.

I can’t shake the feeling that the Huskies’ limited depth will become a problem against the fast-paced Hawkeyes, especially with only four days between games instead of the usual week for the men’s teams. UConn’s key players have been playing heavy minutes, and if the Hawkeyes find their groove, fatigue could set in during the later stages of the game.

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Analysis of the UConn vs. Iowa spread and Over/Under

When the Iowa vs. UConn matchup was first announced, Iowa was favored by 3 points. However, the Hawkeyes are now favored by 2.5 points across most of our top sportsbooks, with only Caesars still offering -3 for the favorites. If you’re looking to bet on the underdog Huskies, Caesars is the best book for you.

Caesars is the sole sportsbook providing a total of 162, while other top sports betting apps are offering 162.5 leading up to the Final Four. It may be challenging to bet the Under when Clark and Bueckers are playing, but opting for the Under seems like the wise choice for those looking to wager on the Over/Under.

Prediction for the UConn-Iowa game was made at 3 p.m. ET on Wednesday.

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