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Aaron Donald of the Los Angeles Rams is featured in our top Rams vs. Colts prediction.
Aaron Donald of the Los Angeles Rams celebrates during the second half against the Seattle Seahawks at Lumen Field. Photo by Steph Chambers/Getty Images/AFP.

The Los Angeles Rams will take on the winless Cincinnati Bengals on Monday night, and we’re using the top NFL odds from our recommended sports betting apps to make our predictions for the Rams-Bengals matchup.

The Rams are off to a solid 1-1 start in 2026, showcasing impressive performances on offense and defense. Their defense is holding opponents to just 281.0 yards per game, while rookie wide receiver Puka Nacua leads the NFL in receptions and targets.

While the Bengals have suffered two losses to AFC North opponents, the status of Joe Burrow for Monday’s game remains uncertain. Is there anyone on the Bengals’ offense we can rely on?

Below are our top Rams-Bengals SGP predictions, with odds sourced from our preferred NFL betting sites. Our level of confidence in each pick is rated on a scale of one to five stars.

Monday Night Football will feature a parlay between the Rams and Bengals.

(Odds via DraftKings)

  • Puka Nacua to have more than 7.5 receptions at odds of +195 ⭐⭐⭐⭐
  • Kyren Williams is expected to rush for more than 59.5 yards with a three-star rating at odds of -105.
  • Rams +3.5 (-150) ⭐⭐⭐⭐

The combined odds are +700 on DraftKings.

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Predictions for Rams vs. Bengals by SGP

Puka Nacua to have more than 7.5 receptions at +195 odds, rated four stars.

Nacua has been incredibly successful with 35 targets in just two games, making it likely that he will have at least eight catches on Monday. The rookie has converted those numerous targets into 25 catches.

The Rams are up against a defense that only allows 195.5 passing yards per game, but Los Angeles relies heavily on their passing game. They average 320.5 passing yards per game, while their rushing game only manages 90.5 yards.

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Nacua’s workload is already incredibly high, with him still among the top five in the league in targets despite the Rams possibly increasing their running plays.

Be cautious about being too greedy and choosing Over 9.5 catches, but definitely consider adding Over 7.5 to any parlay with the great price being offered.

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Kyren Williams to rush for over 59.5 yards (-105) with a three-star rating.

Now that Cam Akers has joined Minnesota, it’s clear that Kyren Williams is the main running back in Los Angeles. Despite the Rams falling behind to the San Francisco 49ers in Week 2, Williams has already rushed 29 times for 104 yards in two games, with 14 carries in that game alone.

The Bengals have struggled mightily against the run in 2026, giving up an average of 192.0 yards per game. In Week 2, three different runners were able to gain at least 40 yards against their defense.

If Burrow plays, the Rams may not rely heavily on their running game since the game could turn into a high-scoring matchup. Despite the Bengals’ struggling offense in 2026, it is unlikely that the Rams will fall behind by a significant margin.

Williams should easily reach this number against a weak run defense without having to share carries.

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Rams +3.5 (-150) ⭐⭐⭐⭐

Note from the editor: Due to the uncertainty surrounding the Bengals’ quarterback situation, the spread is rapidly changing. Some of our top sportsbooks now have the Rams at +1.5, but DraftKings, Caesars, and bet365 still offer +2.

Due to the uncertainty surrounding the Bengals’ offense, it is difficult to confidently choose any player props tied to the team. Even if Burrow plays, the Rams could still come out on top. Therefore, we are opting for a more cautious approach.

Assuming Burrow is on the field, the Rams are poised to keep this game close, potentially within a field goal. The Rams have looked strong in the first two weeks, particularly on defense, holding two top NFL offenses (Seahawks and 49ers) to just 281.0 total yards.

There are numerous factors at play in this game, but one thing is clear – the Bengals’ offense is struggling. Whether Burrow plays or not, we don’t believe they will be able to cover the spread, even if they show improvement from their last two games.

SGP picks for Rams vs. Bengals were made on 09/25/2026 at 9:44 a.m. ET.

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Related pages

  • Top Sports Betting Sites with the Best Promotions (Available in the U.S. only)