Week 3 NFL Predictions: Could the Buccaneers Pull off an Upset Against the Eagles?
The Denver Broncos are looking to secure a crucial road win as they face the Miami Dolphins in Week 3, making them a top pick for an NFL upset based on the latest odds. Despite it being mid-September, the Broncos are in dire need of a victory.
Despite losing their first two games by just 3 points combined, head coach Sean Payton has yet to completely turn things around for the Denver Broncos. Their next challenge comes in the form of a road game against the 2-0 Miami Dolphins, where they are considered full touchdown underdogs. However, we believe the Broncos have what it takes to rise to the occasion.
Below are our top NFL upset selections for Week 3, with odds sourced from our preferred NFL betting platforms. Our level of confidence in each pick is rated on a scale of 1 to 5 stars.
Surprise NFL picks for Week 3
- Titans are set to face the Browns with odds of +150 via BetRivers.
- Broncos are the underdogs with odds of +245 according to FanDuel, playing against the Dolphins ⭐⭐⭐.
- Buccaneers are the underdogs at +195 odds according to BetRivers, facing off against the Eagles ⭐⭐⭐
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NFL upset predictions
Titans moneyline against Browns (+150 odds on BetRivers) ⭐⭐⭐⭐
After an eight-game losing streak dating back to last season, the Tennessee Titans secured a 27-24 overtime victory against the Los Angeles Chargers last week. Ryan Tannehill played a key role in the win, with an impressive performance of 20 completed passes out of 24 attempts for 246 yards, a touchdown, and no interceptions. The Titans also exhibited a newfound ability to make big plays on offense, including two passing plays of 49 yards or more.
Next, they are on their way to face the Cleveland Browns team, who are currently dealing with the absence of star running back Nick Chubb due to a serious knee injury suffered on Monday night in Pittsburgh. Although Jerome Ford had a good performance as a replacement against the Steelers, rushing for 106 yards and scoring a touchdown, he is not as impactful as Chubb. This could be problematic against the Tennessee defense, known for their ability to shut down the running game.
Deshaun Watson is under immense pressure to lead the Browns’ offense, but he has not proven capable of doing so since coming back from suspension last season. In Cleveland’s recent loss to the Steelers, Watson’s turnovers directly contributed to over half of the points scored by Pittsburgh. Tennessee has a strong track record as a road underdog, going 7-2-1 against the spread in their last 10 games in that position. The Titans are poised to pull off another upset in what is expected to be a close, low-scoring game.
Our Green Finnian is also leaning towards Tennessee in his prediction for the Titans-Browns game. To see more of our NFL predictions for Week 3, be sure to check out our website.
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Bet on the Broncos moneyline against the Dolphins with odds of +245 from FanDuel, rated three stars.
The Broncos have started the season disappointingly once again, but there is a silver lining this time. Russell Wilson and the offense are performing well, leading the NFL in points per possession. However, the defense, usually strong, has allowed late leads to slip away in Week 1 against Las Vegas and squandered an early 18-point advantage in last week’s loss to Washington.
There are few situations in the NFL more advantageous than supporting a playoff contender that is 0-2 and aware that a third consecutive loss would likely end their postseason aspirations. Taking the game on the road could benefit the struggling Denver defense, as they look forward to the opportunity to stop Tua Tagovailoa and the Miami offense. Additionally, the Broncos may have an edge on offense due to their familiarity with the defensive strategies of Miami’s coordinator, Vic Fangio, who used to coach in Denver.
Miami’s offense struggled against Bill Belichick and the New England Patriots last week, limiting Tagovailoa to 249 passing yards compared to the nearly 500 he put up in the season opener against the Chargers. Additionally, Tua may be without one of his top receivers as Jaylen Waddle remained in concussion protocol on Wednesday, meaning he was unable to practice all week.
Wood predicts that the Broncos will win and cover the spread in the Broncos-Dolphins matchup.
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BetRivers is offering +195 odds for the Buccaneers ML against the Eagles, which is a three-star bet.
After Tom Brady retired, doubts arose about the Tampa Bay Buccaneers’ ability to maintain their playoff hopes. However, the team has proven resilient thanks to a roster of experienced veterans who were instrumental in their Super Bowl win just three years ago. Particularly impressive is the defense, which ranks eighth in points allowed and second in rushing yards surrendered. This demonstrates the team’s competitiveness even without a legendary quarterback like Brady.
Despite ranking second in the NFL in scoring, Jalen Hurts and the Eagles’ offense have not shown the same potency as last year’s Super Bowl team. Speculation has arisen that Hurts may be playing injured, as he has only averaged 161 passing yards in the first two weeks. While they were successful running the ball against the Vikings, Tampa Bay’s strong defense will present a tougher challenge for the Eagles.
Baker Mayfield’s stellar showing for the Buccaneers has been supported by their solid defense, enabling him to play it safe and steer clear of unnecessary risks. With nearly 500 passing yards and three touchdowns, Mayfield has yet to throw an interception this season. The Buccaneers’ potential to pull off an upset victory as underdogs on Monday night hinges on Mayfield’s knack for avoiding mistakes that could give the struggling Philadelphia Eagles’ passing game an advantage with good field position. A flawless performance from Mayfield could significantly improve the Buccaneers’ odds of success.
Allen Byron, one of our own, is also favoring Tampa in this matchup. He predicts that they will cover a 6.5-point spread in the Eagles-Buccaneers game.
NFL upset predictions were made on 9/20/2026 at 8:46 p.m. ET.
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