Week 16 NFL Odds: Top Super Bowl Contenders Face Off on Christmas Day
The NFL has blessed us with a great holiday gift – games every Thursday, Saturday, Sunday, and Monday. Let’s take a fresh look at the Week 16 odds and betting lines from top NFL betting sites.
The Thursday Night Football game in Week 16 features the New Orleans Saints visiting the Los Angeles Rams, two NFC teams battling for postseason positions. As of Week 15, the Rams currently hold the final NFC Wild Card spot, edging out the Saints in the standings.
On Saturday, there will be two AFC games as the Cincinnati Bengals travel to face their AFC North rivals, the Pittsburgh Steelers, while the Los Angeles Chargers host the Buffalo Bills.
Sunday’s match-up between the Dallas Cowboys and Miami Dolphins, as well as Monday’s game between the San Francisco 49ers and Baltimore Ravens, will feature major contenders facing off against each other. These games are sure to have an impact on the Super Bowl odds. The Ravens and 49ers, who are hosting their games, currently have the best odds of winning their conferences.
Take a more in-depth look at the NFL Week 16 odds offered by our top sports betting websites.
The odds and lines for Week 16 of the NFL games are now available.
It is beneficial to place bets on the early NFL odds in order to beat the closing line. Waiting until kickoff to make picks makes it harder to find advantages and get the best numbers on most bets.
Starting to monitor the NFL opening odds early each week is crucial for long-term success. Taking a proactive approach is key.
Top NFL Week 16 point spreads
(Odds via bet365)
| Game | Spread (Dec. 18) | Opening Spread (Dec. 13) |
|---|---|---|
| Saints vs. Rams | Rams -4 | Rams -4 |
| Bengals vs. Steelers | Steelers +2.5 | Steelers -1.5 |
| Bills vs. Chargers | Chargers +13.5 | Chargers +9.5 |
| Browns vs. Texans | Texans -2.5 | Texans -1.5 |
| Lions vs. Vikings | Vikings +3 | Vikings +3 |
| Packers vs. Panthers | Panthers +4.5 | Panthers +4.5 |
| Colts vs. Falcons | Falcons +2 | Falcons -1.5 |
| Seahawks vs. Titans | Titans +2.5 | Titans +2 |
| Commanders vs. Jets | Jets -3 | Jets -3 |
| Jaguars vs. Buccaneers | OFF | Buccaneers +2.5 |
| Cardinals vs. Bears | Bears -4.5 | Bears -3 |
| Cowboys vs. Dolphins | Dolphins -1.5 | Dolphins -1.5 |
| Patriots vs. Broncos | Broncos -5.5 | Broncos -5.5 |
| Raiders vs. Chiefs | Chiefs -10 | Chiefs -10.5 |
| Giants vs. Eagles | Eagles -10.5 | Eagles -10.5 |
| Ravens vs. 49ers | 49ers -5.5 | 49ers -4.5 |
In Week 16, there are currently six teams listed as home underdogs, with the possibility of more. Additionally, there are seven games with a spread of three points or less, and five games with a spread of two points or less.
Three games have spreads of more than a touchdown on the opening lines, with the Bills, Eagles, and Chiefs all needing to cover more than seven points. Week 15 did not see any additions to the list, but a dominant win by the Bills and a poor showing by the Chargers has resulted in the largest spread of the week, with Buffalo giving up 13.5 points on the road.
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Top NFL Week 16 moneylines
(odds via FanDuel)
| Game | Moneyline (Dec. 18) | Opening Moneyline (Dec. 13) |
|---|---|---|
| Saints vs. Rams | Rams -200 | Rams -196 |
| Bengals vs. Steelers | Steelers +110 | Steelers -112 |
| Bills vs. Chargers | Chargers +590 | Chargers +390 |
| Colts vs. Falcons | Falcons +106 | Falcons -116 |
| Packers vs. Panthers | Panthers +180 | Panthers +188 |
| Browns vs. Texans | Texans -136 | Texans -116 |
| Lions vs. Vikings | Vikings +144 | Vikings +130 |
| Commanders vs. Jets | Jets -158 | Jets -148 |
| Seahawks vs. Titans | Titans +116 | Titans +108 |
| Jaguars vs. Buccaneers | Buccaneers -108 | Buccaneers +122 |
| Cardinals vs. Bears | Bears -205 | Bears -174 |
| Cowboys vs. Dolphins | Dolphins -120 | Dolphins -112 |
| Patriots vs. Broncos | Broncos -275 | Broncos -240 |
| Raiders vs. Chiefs | Chiefs -480 | Chiefs -500 |
| Giants vs. Eagles | Eagles -520 | Eagles -590 |
| Ravens vs. 49ers | 49ers -205 | 49ers -196 |
The Eagles, Chiefs, and Bills are the top favorites to start Week 16, which is no surprise considering they have healthy superstar quarterbacks who are potential Super Bowl contenders. The two top favorites for NFL MVP are facing off on Monday Night Football, with the 49ers, led by QB Brock Purdy, listed as -205 home favorites against the Ravens, led by QB Lamar Jackson.
Top NFL Week 16 Over/Under Bets
(odds via DraftKings)
| Game | Over/Under (Dec. 18) | Opening Over/Under (Dec. 13) |
|---|---|---|
| Saints vs. Rams | 44.5 (-110/-110) | 44.5 (-110/-110) |
| Bengals vs. Steelers | 38 (-110/-110) | 39.5 (-110/-110) |
| Bills vs. Chargers | 42.5 (-110/-110) | 40.5 (-110/-110) |
| Colts vs. Falcons | 44.5 (-110/-110) | 43 (-110/-110) |
| Browns vs. Texans | 42 (-110/-110) | 41 (-110/-110) |
| Packers vs. Panthers | 36 (-110/-110) | 36 (-110/-110) |
| Seahawks vs. Titans | 42.5 (-110/-110) | 44 (-110/-110) |
| Lions vs. Vikings | 47 (-110/-110) | 46 (-110/-110) |
| Commanders vs. Jets | 38 (-110/-110) | 40 (-110/-110) |
| Jaguars vs. Buccaneers | 44.5 (-110/-110) | 44.5 (-110/-110) |
| Cardinals vs. Bears | 44.5 (-110/-110) | 43.5 (-110/-110) |
| Cowboys vs. Dolphins | 51 (-110/-110) | 52 (-110/-110) |
| Patriots vs. Broncos | 36.5 (-110/-110) | 36 (-110/-110) |
| Raiders vs. Chiefs | 43 (-110/-110) | 42 (-110/-110) |
| Giants vs. Eagles | 43.5 (-110/-110) | 44 (-110/-110) |
| Ravens vs. 49ers | 45.5 (-110/-110) | 45 (-110/-110) |
Week 16 continues the trend of low scoring games as the season advances, with many backup quarterbacks playing and poor weather conditions. Only one game is expected to have over 50 points, while four games are predicted to have less than 40 points.
The two games are within the number range of 43-44.
NFL betting odds pages
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- Check out our DraftKings Review and use the DraftKings Promo Code
21 and older. If you have a gambling problem, please call 1-800-GAMBLER. Bonuses are not valid in Ontario.
Related pages
- Top Sports Betting Sites with the Best Promotions (Available in the U.S. only)
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