Chargers vs. Raiders NFL Player Props, Odds

Aidan O'Connell #4 of the Las Vegas Raiders is pressured by Sebastian Joseph-Day #51 and Khalil Mack #52 of the Los Angeles Chargers as we make our Chargers vs. Raiders player prop picks and predictions for Thursday Night Football. — Aidan O’Connell #4 of the Las Vegas Raiders is pressured by Sebastian Joseph-Day #51 and Khalil Mack #52 of the Los Angeles Chargers during the third quarter at SoFi Stadium on October 01, 2026 in Inglewood, California. Photo by Kevork Djansezian/Getty Images via AFP.

Thursday Night Football will feature backup quarterbacks as the Los Angeles Chargers take on the Las Vegas Raiders in Week 15. We have you covered with our top player props for the Chargers vs. Raiders game, based on the best TNF odds.

For the second week in a row, the Los Angeles Chargers and Las Vegas Raiders will have their backup quarterbacks go head-to-head on Thursday Night Football. Both teams are fighting to stay in the AFC playoff race and will face off in a Week 15 primetime showdown.

With Justin Herbert (finger) sidelined for the rest of the season, the Chargers turn to longtime backup Easton Stick to make his first career NFL start. Check out King Orson’s predictions for Stick’s performance in player props.

In the meantime, Raiders’ rookie QB Aidan O’Connell is set to make his seventh start of the season, following his last shutout at home in Week 14. Stay tuned for Kelly Irvin’s player props for Aidan O’Connell.

In our Week 15 NFL predictions, we are providing our best player props for the Chargers vs. Raiders game on Thursday Night Football. These predictions are based on a 1-to-5-star scale of confidence and NFL odds from top betting sites.

Chargers vs. Raiders NFL player props: Thursday Night Football

Michael Mayer longest reception Over 11.5 yards (-110 via BetMGM) ⭐⭐⭐⭐

Mayer, drafted 35th overall by the Raiders in April, has taken some time to make his mark as a rookie tight end, as is typical. However, he has shown consistent ability to make at least one big play. Heading into Week 15, Mayer is poised to deliver another impactful performance in an ideal position.

Although the Notre Dame player has failed to meet the yardage prop total of 19.5 in nine out of 13 games, he has caught at least one pass for 12 or more yards in six of his last nine games. This streak has continued over the last three weeks with O’Connell as the quarterback.

He is expected to have another good game against the Chargers defense, which is ranked fifth-worst in allowing receptions (74) and receiving yards (784) to tight ends. In Week 14, Los Angeles allowed second-year tight end Lucas Krull, who had been on the Denver Broncos’ practice squad for most of the season, to gain 35 yards on his first professional catch.

The Chargers have given up a catch of at least 12 yards to an opposing tight end in eight out of their nine games since facing these teams in Week 4. This trend is likely to continue on Thursday.

Evans Santiago provides further analysis on Mayer and gives his prediction for an anytime touchdown scorer in Thursday Night Football.

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Khalil Mack Over 0.75 sacks (-145 via DraftKings) ⭐⭐⭐

This is equally a showcase of Mack’s talent and a critique of the Raiders’ struggling offensive line, which was outplayed in the first matchup between these teams in early October.

In that game, Las Vegas surrendered a record-breaking seven sacks, with six of them coming from Mack, who dominated his former team. This performance is consistent with his career pattern, as the All-Pro edge rusher has now accumulated a total of 10 sacks in five matchups against the Raiders.

Mack went sackless in Week 14 but still managed to generate five pressures for the fourth consecutive week. In the previous three weeks, he had multiple sacks in each game. On the other hand, the Minnesota Vikings dominated Las Vegas, sacking O’Connell four times in a shutout victory.

The Raiders’ struggling offensive line was already facing injuries when they lost center Andre James to an ankle injury, making it unlikely he will play on a short week. This sets up a favorable matchup for Mack, who is heavily favored at -180 on bet365 to get a sack on Thursday.

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Player props for Thursday Night Football between the Chargers and Raiders were set on Wednesday at 2:05 p.m. ET.

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Written By:
Morgan Xaviero

Morgan Xaviero is a publishing editor and lead writer for Underscoreg Review. An award-winning writer, reporter, and editor with a decade of sports media experience, “C-Jax” has worked with ESPN, Forbes, theScore, and various daily newspapers before joining the Underscoreg Review team. He’s a proud graduate of the University of North Carolina, where he served as a beat writer for the Tar Heels’ championship run through the NCAA men’s basketball tournament in 2017. Jackson has spent the last five years covering sports betting as a predictive analyst, features writer, and industry reporter. Since joining the team in 2026, he’s played a key role in Underscoreg Review’s coverage of the Super Bowl, March Madness, and NBA playoffs while serving as the lead writer for the growing WNBA and NASCAR betting scenes. Though he’s cashed some big bets over the years — including Lamar Jackson to win MVP (twice) — he’s still haunted by enough second-place bet slips to wallpaper his home office. While Jackson is a committed “process over results” bettor with a keen eye for advanced stats and subtle bias in futures markets, he also embraces sports betting as a vehicle for entertainment and personal investment. He’s written about everything from hot dogs to groundhogs and still hasn’t forgiven his “inside source” for a sabotaged bet on the Gatorade color in Super Bowl LV.