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Premier League Odds & Best Bets This Week: Schedule, Picks for Matchday 26

Young Quigley

Updated on March 3, 2026 at 8:20 AM EST. Read time: 4 minutes and 39 seconds. Links to Twitter and Google News.

Premier League Best Bets
Premier League Best Bets

Matchday 26 of the Premier League begins on Saturday morning with a packed schedule. Manchester City will face Newcastle United in the early match, looking to secure a win and narrow the gap on league leaders Arsenal. Stay tuned for our top betting picks for Matchday 26 in the Premier League, featuring the most favorable EPL odds.

On Sunday, Anfield will host a showdown between two major rivals in the league. Despite trailing Manchester United by 10 points, Liverpool enters the match with momentum from a 2-0 victory against Wolves. United has been the top-performing team since the Premier League resumed after the World Cup hiatus.

Graham Potter will be looking to help Chelsea return to their winning form when they face Leeds at Stamford Bridge. With the Whites having the poorest away record in the league, this match could be the ideal chance for Potter to make a turnaround.

These are our top Premier League betting picks for Matchday 26, with odds from DraftKings, Caesars, and PointsBet. Confidence level is rated on a scale of 1 to 5 stars.

Explore our top soccer betting picks for this week from the top leagues in Europe!

Premier League schedule and odds for Matchday 26

(odds via FanDuel)

  • Manchester City (-210) vs. Newcastle (+550)
  • Arsenal (-470) vs. Bournemouth (+1300)
  • Chelsea (-160) vs. Leeds (+460)
  • Wolves (+230) vs. Tottenham (+120)
  • Liverpool (+135) vs. Manchester United (+185)

Premier League best bets for Matchday 26

  • Moneyline: Aston Villa (+105 via DraftKings and PointsBet) vs. Crystal Palace⭐⭐⭐
  • Spread: Arsenal (-2) vs. Bournemouth (+105 via DraftKings) ⭐⭐⭐⭐
  • Total: Brentford vs. Fulham Over 2.5 goals (-115 via PointsBet) ⭐⭐⭐
  • Prop: Southampton vs. Leicester both teams to score, Southampton win (+450 via Caesars) ⭐⭐⭐

Take a look at our top Champions League betting odds.

Premier League top picks

Moneyline: Aston Villa (+105) vs. Crystal Palace (via DraftKings and BetMGM) ⭐⭐⭐

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Crystal Palace has not secured a victory in the Premier League in 2026, extending their winless streak to eight games. Despite this, they have managed to remain unbeaten in their last three matches with three draws, and have also drawn five of their last six games.

In his 11 Premier League matches as Villa manager, Unai Emery has overseen a scoring team in every game. Under his leadership, the Villans have secured six victories and suffered four defeats. Despite back-to-back 4-2 losses at home, Villa has only lost once to Palace at home in the Premier League, a decade ago.

In this matchup between the 11th and 12th place teams, Villa, under Emery’s leadership, is pushing for European qualification with 14 games left in the season. Coming off a road win against Everton last week, they are expected to take advantage of Palace’s struggles and emerge victorious in this game, which heavily favors the home team.

All of our top sportsbooks agree that Villa is the favorite in this play, with each of them giving them favorable odds. PointsBet lowered their odds from +105 on Wednesday to +100 on Thursday. Caesars also decreased their odds from +105 to +102 during the same time frame. DraftKings has kept their odds steady, while BetMGM went against the trend and raised their odds to +105.

Spread: Arsenal (-2) vs. Bournemouth (+105 via DraftKings) ⭐⭐⭐⭐

In order for Arsenal to secure the Premier League title, they must win these crucial games. They convincingly defeated Everton 4-0 at the Emirates on Wednesday, and now all eyes are on them to perform against the Cherries this Saturday.

Arsenal has always won at home against Bournemouth in every competition they have faced off in, and Bournemouth has never managed to keep a clean sheet against Arsenal in the Premier League.

Bournemouth has struggled since the World Cup break, scoring the fewest goals and earning the fewest points in the competition. They have also conceded the most goals in the league this season (48), with only Manchester City (64) and Arsenal (56) scoring more.

This week, my top pick is a four-star play due to the impressive form of both teams. Bournemouth must secure victories against their direct rivals to avoid relegation this season. However, Arsenal’s superior class, strong attack, and second-best defense in the league make them clear favorites in this match. DraftKings is the only bookmaker offering a spread of -2 for this game.

Total: Brentford vs. Fulham Over 2.5 goals (-110 via PointsBet) ⭐⭐⭐

Brentford is currently on an 11-game unbeaten streak in the Premier League, the longest in the competition. Fulham, who have won five away matches this season, are equaling their record for top-flight road wins in a single campaign as they head to face their neighbors.

Both teams are skilled at scoring, with Brentford having scored 37 goals and Fulham close behind with 36. The Cottagers are just six points away from a Champions League spot, a remarkable feat for a newly promoted team with 13 games left in the season.

As we approach this matchday, Harry Kane leads with eight London derby goals, followed by Aleksandar Mitrovic and Ivan Toney with four each in this season’s competition.

Support the goals in this competition. PointsBet now has improved odds of -110, providing the best value for betting on the Over. Caesars is offering a price of -120, while BetMGM has lowered their odds to -118 from Wednesday to Thursday. It’s advisable to take advantage of the -110 odds as there is still time before the game on Monday and odds may change.

Prop: Southampton vs. Leicester both teams to score, Southampton win (+450 via Caesars) ⭐⭐⭐

Both Southampton and Leicester were embarrassed by lower league teams in FA Cup matches at their home stadiums this week. Despite being at the bottom of the Premier League, Southampton is within four points of safety. These are the crucial games they must win to avoid relegation.

Southampton have not won any of their last eight Premier League home games, drawing two and losing six. They have lost their last five in a row, but have never lost six consecutive home games. Leicester have conceded more away goals than all but two teams in the league this season. Southampton defeated Leicester in the previous meeting in August, coming from behind to win 2-1.

Anticipate plenty of goals in this match, as both teams are battling to secure their place in the Premier League. With time running out for the Saints, this home game holds even more importance. This prop bet carries high odds, with consistent pricing across our top bookmakers. Caesars is offering a little extra juice at +450.

Best bets for the Premier League were placed on 03/02/2026 at 8 a.m. ET.

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Written By:
Young Quigley
Young Quigley has worked in the sports industry for more than 20 years. He’s reported on Premier League games for BBC radio and continues to cover the league, as well as other high-profile soccer competitions such as the UEFA Champions League. He is a founding member of the NFL Writers Network with NFL Europe, having covered every NFL London game since 2014 and multiple Super Bowls. Anthony has also reported on the Germany games in Munich and Frankfurt. His book, “The Greatest American Football Story That Has Never Been Told”, has been an Amazon bestseller for American Football and Sports History publications. He is a member of the Professional Football Researchers Association. Anthony started writing for betting companies in 2018, working with some of the world’s largest gambling sites. He is an avid bettor on soccer and football, using multiple apps as he targets the best value on props and plays. Anthony is the host of the “TransAtlantic Sports Show” podcast and runs a weekly parlay feature on his YouTube channel throughout the NFL season. He has appeared on leading international podcasts such as the BBC World Service’s Sportshour, the Nat Coombs Show, and the Irish NFL Show. Anthony holds a bachelor’s degree in media from Sheffield Hallam University.