Week 4 NFL Betting Odds: Spreads, Moneyline, and Over/Under Lines
In Week 4 of the NFL, fans can look forward to an exciting AFC East rivalry game between two top Super Bowl contenders in the AFC. Let’s take a closer look at the Week 4 odds and betting lines offered by our top NFL betting sites.
Week 4 of the NFL season features a lineup of intense rivalry games that will have a major impact on deciding division champions. On Thursday Night Football, the Detroit Lions will travel to Lambeau Field to take on the Green Bay Packers in a rematch of last season’s Week 18 showdown, where the Lions emerged victorious, knocking the Packers out of the playoffs.
The Miami Dolphins will be facing the Buffalo Bills at Highmark Stadium on Sunday afternoon, a game that I believe is the most anticipated of Week 4. The Bills are currently favored by 2.5 points over the Dolphins, a line that is sure to attract a lot of attention from fans of both teams.
We will examine the opening odds for Week 4 of the NFL season on our top sports betting apps.
Week 4 NFL odds and betting lines
It is beneficial to place bets on NFL markets early in order to take advantage of favorable odds and beat potential line movements. Waiting until Sunday to make NFL picks can make it harder to find opportunities for successful bets and secure the best prices.
It is crucial to begin tracking the NFL opening odds weekly as soon as possible in order to enhance your overall success in sports betting.
Top NFL Week 4 betting lines
| Game | Opening Spread (Sept. 20) | Spread (Sept. 25) |
|---|---|---|
| Lions vs. Packers | Pick | Lions -2 |
| Falcons vs. Jaguars | Jaguars -3 | Jaguars -3 |
| Rams vs. Colts | Rams -1 | Colts -1 (-105) |
| Buccaneers vs. Saints | Saints -3.5 | Saints -3 |
| Commanders vs. Eagles | Eagles -7 | Eagles -7 |
| Steelers vs. Texans | Steelers -4 | Steelers -3.5 (-105) |
| Bengals vs. Titans | Bengals -1 | Titans -1.5 |
| Ravens vs. Browns | Ravens -1.5 | Browns -2 |
| Broncos vs. Bears | Broncos -2 | Broncos -3.5 |
| Dolphins vs. Bills | Bills -3 | Bills -2.5 (-120) |
| Vikings vs. Panthers | Vikings -3 | Vikings -3 |
| Raiders vs. Chargers | Chargers -4.5 | Chargers -4.5 |
| Patriots vs. Cowboys | Cowboys -7.5 | Cowboys -7 |
| Cardinals vs. 49ers | 49ers -14.5 | 49ers -14 |
| Chiefs vs. Jets | Chiefs -7 | Chiefs -9 |
| Seahawks vs. Giants | Seahawks -1.5 | Seahawks -1.5 |
The Baltimore Ravens, who were originally favored by 1.5 points over the Cleveland Browns on the road in Week 4, have now switched positions with the Browns as the underdogs due to their loss to the Indianapolis Colts in overtime and various injuries. The Browns are currently listed as 2-point favorites over the Ravens.
Top NFL Week 4 Moneyline Picks
| Game | Opening Moneyline (Sept. 20) | Moneyline (Sept. 25) |
|---|---|---|
| Lions vs. Packers | Packers (-122) | Lions (-118) |
| Falcons vs. Jaguars | Jaguars (-148) | Jaguars (-155) |
| Broncos vs. Bears | Broncos (-122) | Broncos (-175) |
| Vikings vs. Panthers | Vikings (-130) | Vikings (-148) |
| Rams vs. Colts | Rams (-120) | Rams (-110) |
| Buccaneers vs. Saints | Saints (-218) | Saints (-148) |
| Commanders vs. Eagles | Eagles (-375) | Eagles (-290) |
| Dolphins vs. Bills | Bills (-180) | Bills (-142) |
| Bengals vs. Titans | Bengals (-118) | Titans (-122) |
| Ravens vs. Browns | Ravens (-120) | Browns (-120) |
| Steelers vs. Texans | Steelers (-198) | Steelers (-170) |
| Raiders vs. Chargers | Chargers (-225) | Chargers (-205) |
| Patriots vs. Cowboys | Cowboys (-360) | Cowboys (-285) |
| Cardinals vs. 49ers | 49ers (-950) | 49ers (-850) |
| Chiefs vs. Jets | Chiefs (-360) | Chiefs (-395) |
| Seahawks vs. Giants | Seahawks (-115) | Seahawks (-120) |
In just Week 4 of the NFL season, we already have a heavy favorite with the Arizona Cardinals at -850 on the moneyline. However, it’s worth noting that the Cardinals recently defeated the Dallas Cowboys in Week 3. They will now face the San Francisco 49ers at Levi’s Stadium in Week 4. Despite initial thoughts of tanking for USC QB Caleb Williams, it seems the Cardinals may be stronger than expected. The Cardinals are currently underdogs at +575 on the moneyline and are getting 14 points on the spread. Both lines have shifted slightly in their favor after their Week 3 victory over the Cowboys.
In Week 4, the Kansas City Chiefs are also huge favorites on the moneyline, with -395 odds against the New York Jets on Sunday Night Football. Unfortunately, the excitement of a primetime matchup was lost when Aaron Rodgers got injured in Week 1. With Zach Wilson leading the Jets, the announcers will have plenty of time in the fourth quarter to discuss Taylor Swift and Travis Kelce.
Top NFL Week 4 Over/Under Picks
| Game | Opening Over/Under (Sept. 20) | Over/Under (Sept. 25) |
|---|---|---|
| Lions vs. Packers | 46.5 (-110/-110) | 45 (-110/-110) |
| Falcons vs. Jaguars | 45.5 (-110/-110) | 43.5 (-110/-110) |
| Ravens vs. Browns | 44.5 (-110/-110) | 41.5 (-110/-110) |
| Bengals vs. Titans | 44 (-110/-110) | 42.5 (-110/-110) |
| Broncos vs. Bears | 44.5 (-110/-110) | 46 (-110/-110) |
| Rams vs. Colts | 45 (-110/-110) | 45 (-110/-110) |
| Dolphins vs. Bills | 49.5 (-110/-110) | 53.5 (-110/-110) |
| Vikings vs. Panthers | 44.5 (-110/-110) | 45 (-110/-110) |
| Steelers vs. Texans | 40.5 (-110/-110) | 41 (-110/-110) |
| Buccaneers vs. Saints | 41 (-110/-110) | 40.5 (-110/-110) |
| Commanders vs. Eagles | 44.5 (-110/-110) | 44.5 (-110/-110) |
| Raiders vs. Chargers | 49.5 (-110/-110) | 50.5 (-110/-110) |
| Cardinals vs. 49ers | 41 (-110/-110) | 42 (-110/-110) |
| Patriots vs. Cowboys | 42.5 (-110/-110) | 41.5 (-110/-110) |
| Chiefs vs. Jets | 45 (-110/-110) | 42.5 (-110/-110) |
| Seahawks vs. Giants | 45 (-110/-110) | 45 (-110/-110) |
The Dolphins-Bills game in Week 4 now has the highest total, jumping from 49.5 to 53.5 due to the Dolphins scoring 70 points against the Broncos in Week 3. Initially, no total exceeded 50 points on the lookahead lines, but the Raiders-Chargers game has also moved into the 50s.
NFL betting odds pages
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Related pages
- Top Sports Betting Websites | Top Promotions for Underscoreg (Available in the U.S. only)
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