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Payton Thorne #10 of the Michigan State Spartans plays against the Ohio State Buckeyes at Spartan Stadium on Oct. 8.
Payton Thorne #10 of the Michigan State Spartans plays against the Ohio State Buckeyes at Spartan Stadium on Oct. 8. Gregory Shamus/Getty Images/AFP

Michigan State has yet to secure a Big Ten victory (0-3) this season as they prepare to face Wisconsin at home on Saturday. See our top picks for the Wisconsin-Michigan State matchup below.

Michigan State Spartans suffered a 49-20 defeat at the hands of Ohio State on their home turf last week. They were unable to cover the 27.5-point spread as underdogs, extending their losing streak to three games in Big Ten play and four games overall.

With a 3-3 record overall and a 1-2 record against conference opponents, Wisconsin heads into Week 7. Their most recent victory was a dominant 42-7 win over Northwestern.

Below are our top selections for the college football game between Michigan State and Wisconsin, with odds provided by DraftKings and FanDuel. Our confidence in each pick is rated on a scale of 1 to 5 stars.

Wisconsin vs. Michigan State Odds

Wisconsin vs. Michigan State Picks

Ms U1012

Wisconsin vs. Michigan State ATS Pick

Wisconsin -7.5 (-104) ★★★★

This season, the Badgers have suffered three defeats, falling to a strong 5-1 Illinois team, the undefeated Ohio State, and a 4-2 Washington State squad that has only lost to ranked opponents. Wisconsin’s offense has scored a total of 191 points so far.

Despite accumulating 155 points this season, the Spartans have only scored 40 points in their last three games and have suffered losses by 11 points or more in four consecutive games.

After the firing of head coach Paul Chryst, the Badgers have seen a resurgence under new coach Jim Leonhard. In their latest game, they racked up an impressive 515 yards of offense, with quarterback Graham Mertz throwing for a career-best 299 yards and five touchdowns. The Spartans, who have been giving up an average of 292 passing yards per game, are likely to struggle against Wisconsin’s strong passing attack.

Wisconsin vs. Michigan State O/U Pick

Under 46.5 (+126) ★★★

This season, Michigan State is scoring an average of 26.2 points per game while Wisconsin is scoring an average of 31.8 points per game. Together, the two teams are averaging a total of 58 points per game.

In their most recent three matchups, the two teams have struggled to collectively score more than 38 points. Michigan State has only scored six points against Wisconsin in their last two meetings, while Wisconsin has managed to score over 30 points in each game.

Michigan State’s struggling offense, which has failed to score more than 20 points in their last three games, will face a tough challenge against a Wisconsin team that has held opponents to fewer than 17 points in four games this season.

Wisconsin vs. Michigan State Prop Pick

Michigan State Over 3.5 1st-quarter points (+115) ★★★★

Michigan State has scored 13 first-half points in each of their last two games, despite not achieving their desired results. They have also managed to put up seven points in the first quarter of both matchups.

Michigan State has only failed to score at least seven points in a first quarter on two occasions – during their losses to Washington and Minnesota.

Wisconsin has given up seven or more points in the first quarter just twice this season. However, in two of their last three games, they allowed Illinois and Ohio State to score in the opening quarter.

Where to Bet on Wisconsin vs. Michigan State Picks

Picks for Wisconsin vs. Michigan State were made on 10/12/2022 at 3:17 p.m.