49ers vs. Bears Week 1 NFL Picks: Can Trey Lance Lead Road Favorites to Victory?
The San Francisco 49ers will visit the Chicago Bears in an NFL Week 1 matchup on Sunday afternoon. Take a look at the odds and trends for this NFC showdown, as well as our predictions for the 49ers-Bears game.
Trey Lance steps onto the field as the starting quarterback for San Francisco for the first time. This game will only be Lance’s third start in his career, as he replaces veteran Jimmy Garoppolo as the leader of the Niners’ offense. The Bears are hoping to bounce back after only winning one game in their last six home games of 2021.
The 49ers secured a 33-22 win during their Week 8 visit to Soldier Field last season, and have emerged victorious in three of their last five matchups against the Bears, all of which took place in Chicago.
These are our favorite picks for the 49ers-Bears NFL game in Week 1, with odds from Pointsbet and FanDuel Underscoreg. Our confidence in each pick is rated on a scale of 1 to 5 stars.
49ers vs. Bears Game Info
Sunday, September 11 at 1 p.m. ETTV: FOXSoldier Field, Chicago, ILWeather: Rainy with a temperature of 75 degrees, 80% chance of precipitation, winds at 9 mph gusting up to 18 mph.
49ers vs. Bears Odds Analysis
At the start of the offseason, the 49ers were initially favored by 6.5 points in the betting line. It later increased to -7.5 before eventually settling back down to -7 at the majority of our top sportsbooks.
The Bears started as +210 underdogs on the moneyline but have since dropped to +250 at PointsBet. However, supporters of the Bears can still find them with +265 moneyline odds on DraftKings.
The Bears had a consistent 6-2-0 record for the Under when playing at home last season, and this trend is not being ignored in the current odds for Sunday’s game. The total has initially been set at 43 at Caesars, but most sportsbooks are now offering a total of 40.5. For those interested in betting the Over, DraftKings has set the number at 40.
49ers vs. Bears Picks
49ers vs. Bears ATS Pick
49ers -6.5 (-107) ★★★★
Lance displayed glimpses of his immense talent in a small sample size during the preseason, shining with a 92-yard rushing performance and a touchdown in the team’s victory over the Green Bay Packers. His ability as a running threat was evident as he racked up 1,100 rushing yards while guiding North Dakota State to the 2020 FCS national championship. Furthermore, Elijah Mitchell, the team’s top rusher from last season, has been cleared to return after being taken off the injury report on Wednesday.
Bears quarterback Justin Fields is facing an even greater challenge as uncertainty looms over rookie receiver Velus Jones Jr.’s status for Sunday. The Chicago receiving corps, which is already without offseason additions David Moore, N’Keal Harry, and Tajae Sharpe, is now in a more difficult position.
49ers vs. Bears O/U Pick
Under 40.5 (-110) ★★★★
Injuries, a strong Bears defense, and the likelihood of rain are all reasons to bet on the Under. While both quarterbacks have something to prove, the Bears’ receiving corps is depleted by injuries and the Niners’ offensive line may not give Lance many chances to shine in the air. Points will be hard to come by in this game.
49ers vs. Bears Prop Pick
Lance Over 40.5 rushing yards (+100) ★★★
In Lance’s first career start last season, the 49ers struggled against the Arizona Cardinals’ tough defense and ultimately lost 17-10. Despite the defeat, Lance showcased his impressive scrambling skills by running for a game-high 89 yards.
With the possibility of rain and the Bears’ strong pass defense, expect Lance to run the ball frequently in Sunday’s game.
Where to Bet on 49ers vs. Bears Picks
These are the sportsbooks that have received the highest ratings:
Picks for the 49ers-Bears game were made on 9/8/2022 at 10 a.m. ET.
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