49ers vs. Seahawks NFL Player Props, Odds: Thanksgiving Picks & Predictions
We are supporting the offenses of the San Francisco 49ers and Seattle Seahawks in our player props for the 49ers-Seahawks NFL game on Thanksgiving night, taking into account the best NFL odds available.
The San Francisco 49ers, with a record of 7-3, and the Seattle Seahawks, at 6-4, are engaged in a heated battle for NFC West supremacy. Their highly anticipated matchup on Thanksgiving night is just another chapter in their intense rivalry. This crucial showdown not only showcases their desire for divisional control but also promises a thrilling and high-stakes game, creating excitement and anticipation for the Thanksgiving evening football lineup.
Will San Francisco and its dominant rushing attack be able to silence the Seahawks’ notorious 12th Man?
In addition to our NFL Thanksgiving predictions and our prediction for the 49ers vs. Seahawks game, we are providing our top player props for the Week 12 matchup between the 49ers and Seahawks. These props are based on odds from our recommended NFL betting sites, with confidence ratings ranging from 1 to 5 stars.
49ers vs. Seahawks NFL player props: Week 12
Christian McCaffrey 2+ rushing touchdowns (+230 via DraftKings) ⭐⭐⭐
Christian McCaffrey has scored a touchdown in every game except for one in 2023, and he has found the end zone multiple times in three out of his last seven games. With the way the Seahawks have been struggling on defense in the red zone, the odds are in McCaffrey’s favor to have a standout performance on Thanksgiving.
Seattle ranks seventh in the league for rushing touchdowns allowed per game at 1.1. With McCaffrey being the Niners’ top weapon in the red zone, I expect Kyle Shanahan to center his offensive strategy around him in a crucial game that could solidify their divisional position.
The odds for CMC to score twice at DraftKings, BetMGM, and FanDuel (+230) are more favorable compared to bet365 (+180) or Caesars (+200).
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Deebo Samuel Over 10.5 rushing yards (-110 via bet365) ⭐⭐⭐⭐
Deebo Samuel had a game where he only had one rushing attempt and lost a yard on the play. This could potentially impact Samuel’s rushing stats for the upcoming Thanksgiving night game.
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In the three games leading up to the Week 11 victory against Tampa Bay, Samuel consistently surpassed a rushing line of 10.5 yards with multiple rushing attempts. Deebo’s explosive abilities make it possible for him to exceed this mark in just one play. I have confidence in Shanahan’s ability to create the perfect opportunity for one of his most versatile weapons to achieve this on Thursday.
While Samuel may have potential for success as a receiver, Allen Byron explains why his quarterback, Brock Purdy, may encounter difficulties in his prop picks.
The rushing yards line is consistent at 10.5 across all top sportsbooks, but the odds differ. Caesars is offering -121 on the Over, which should be avoided. The best odds are found at bet365, with the Over priced at -110.
Tyler Lockett Over 4.5 receptions (-120 via DraftKings) ⭐⭐⭐⭐
With Kenneth Walker injured and uncertain for the game, the Seahawks may struggle to run the ball against the NFL’s third-best run defense. This could lead to more reliance on dependable receivers in this important rivalry matchup, with Tyler Lockett likely to be a key player in the passing game.
While Lockett may have a tough challenge against San Francisco’s strong secondary in terms of yardage, I believe he will still be able to make at least five receptions in the game. Geno Smith will likely rely on Lockett during crucial third down situations, as the wide receiver has a knack for finding open spaces in the defense to keep drives alive.
To improve your chances, stick to DraftKings, BetMGM, or Caesars for prop bets with odds between -120 and -121, and avoid odds of -140 or worse at FanDuel and bet365.
Player props for the 49ers-Seahawks game were created on Wednesday at 1:45 p.m. ET.
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