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Joe Burrow of the Cincinnati Bengals reacts after throwing a touchdown pass against the New York Jets.
Joe Burrow of the Cincinnati Bengals reacts after throwing a touchdown pass against the New York Jets. Photo by Sarah Stier/Getty Images via AFP.

The Buffalo Bills are favored to win at home against the Cincinnati Bengals in the AFC Divisional Round game at Highmark Stadium on Sunday. Check out our NFL odds analysis for this exciting showdown between two red-hot teams vying for a spot in the Super Bowl.

Despite being the No. 1 seed in the AFC, the Kansas City Chiefs will face tough competition from the Bills and Bengals, who are both on impressive winning streaks as they prepare to clash in the divisional round at Highmark Stadium on Sunday.

Cincinnati maintained their undefeated streak since October by defeating the Baltimore Ravens 24-17 last week, while the Bills secured their eighth consecutive win with a narrow 34-31 victory over the Miami Dolphins.

Check out the top NFL odds for the AFC Divisional Round game between the Bengals and Bills from our trusted sportsbooks.

Explore our top NFL betting picks and recommended NFL betting platforms.

Bengals vs. Bills Odds

Take a look at our odds for the Super Bowl and the Super Bowl MVP.

Bengals vs. Bills Moneyline

Buffalo has dominated at Highmark Stadium, winning 11 of its last 12 games. They are heavily favored to please their fans once more. If you choose to bet on the Bills to win, you will have to wager more than double the amount. DraftKings is offering the best odds for Buffalo at -245 on the Moneyline compared to other sportsbooks.

If you’re looking to bet on the Bengals, who have been undefeated since October, PointsBet is the best place to find a great underdog price of +220.

Bengals vs. Bills Spread

Many sportsbooks initially set Buffalo as a 4-point favorite, marking the smallest home favoritism the Bills have received all season. However, early bettors found this number too low, causing the point spread to shift to a near consensus of Buffalo -6. As of Sunday morning, DraftKings and FanDuel still have the line at Bills -5.5.

The Bills have won 11 of their last 12 games at Highmark Stadium, but they have only covered the spread in one of their last six games as the home team. Two of their last three home wins have been by just a field goal. On the other hand, Cincinnati has covered the spread in eight straight games as an underdog, continuing a strong 20-3 against-the-spread streak that dates back to last year.

Bengals vs. Bills Over/Under

The Over/Under for the Bills-Bengals game is set at 48.5 at our top-rated sportsbooks, which is lower than the total for the Week 17 meeting in Cincinnati that was postponed due to Damar Hamlin’s cardiac arrest.

Despite recent trends, both the Bengals and Bills are facing a relatively high total of 48.5, which is unusual considering their past games where the Over/Under was set lower. The Bills, in particular, have had lower totals in their last six games, all set at 45 or less.

Bengals vs. Bills Trends

Cincinnati Bengals

  • 12-3 ATS in their last 15 games
  • 9-0 straight-up in their last nine games
  • 7-1 ATS in their last eight road games
  • 6-0 to the Under in their last six games as underdogs

Buffalo Bills

  • 8-0 SU in their last eight games
  • 2-5 ATS in their last seven home games
  • 5-1 to the Over in their last six home games
  • 4-0 to the Over in their last four home games

Bengals vs. Bills Game Info

Who is favored to win between Bengals and Bills?

The Bills have -225 odds to win against the Bengals on the Moneyline.

What is the betting line for Bengals and Bills?

The Bengals are 5-point underdogs against the Bills and the total points expected in the Bengals-Bills game is set at 48.5.

How to watch Bengals and Bills

The Bills will face off against the Bengals in a televised game on CBS, with kickoff scheduled for 3 p.m. ET at Highmark Stadium.

How to bet on Bengals and Bills?

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