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Brock Purdy of the San Francisco 49ers throws the ball against the Arizona Cardinals at Levi's Stadium on Jan. 08.
Brock Purdy of the San Francisco 49ers throws the ball against the Arizona Cardinals at Levi’s Stadium on Jan. 08. Photo by Ezra Shaw/Getty Images via AFP.

The top-tier secondary of the Eagles will provide a tough challenge for Brock Purdy, who has managed to avoid interceptions in the NFL playoffs so far. Check out our championship game parlay picks using the top NFL odds available.

The San Francisco 49ers, Philadelphia Eagles, Cincinnati Bengals, and Kansas City Chiefs are widely regarded as the top four teams in the NFL. As a result, it’s not surprising that the point spreads for this weekend’s conference championship games are expected to be very close. It’s highly probable that both games will start with point spreads of less than a field goal.

Instead of risking it all on games with uncertain outcomes, you may want to combine multiple probable results in a parlay to increase your chances of a profitable return.

We are providing our top NFL parlay picks for the conference championship weekend, based on odds from FanDuel and rated on a 1 to 5-star scale for confidence.

Take a look at our predictions for the 49ers vs. Eagles and Bengals vs. Chiefs matchups, as well as our top bets and player prop selections.

NFL parlay picks for Conference Championships

  • Brock Purdy to throw an interception (-162) vs. Eagles
  • Jerick McKinnon 25+ receiving yards (-154) vs. Bengals
  • Chiefs +7.5 (-390) vs. Bengals

Combined odds: +248

Take a look at our odds for the Super Bowl and Super Bowl MVP.

NFL parlay predictions

Brock Purdy to throw an interception (-165) ⭐⭐⭐⭐

Despite Mr. Irrelevant’s clean record of no interceptions in the playoffs so far, he will be up against the toughest challenge of his NFL career with the Eagles defense. Philadelphia’s defense, which ranked first against the pass this season, has been averaging an interception per game and possesses a strong pass rush that can pressure Mr. Irrelevant into making quicker decisions than he may prefer.

No rookie quarterback has made it through an entire postseason with more than 14 pass attempts without throwing an interception. Given the likelihood of this happening, I believe Purdy’s luck will run out this week.

Jerick McKinnon 25+ receiving yards (-154) ⭐⭐⭐⭐

Due to an ankle injury, Chiefs quarterback Patrick Mahomes will have limited mobility in the pocket, forcing him to rely more on short passes. This will likely result in an increased workload for Jerick McKinnon catching passes out of the backfield.

The Chiefs should consider increasing McKinnon’s involvement in the offense, especially since he was named the AFC Offensive Player of the Month in December. Despite not getting many touches in the divisional round against Jacksonville, McKinnon had been consistently productive in previous games, recording at least 26 receiving yards in four of his last five games and nine of the previous 12. By betting on the over for McKinnon’s receiving yards line of 25-plus, we can capitalize on his potential impact on the game.

Chiefs +7.5 alternate spread (-390) ⭐⭐⭐⭐⭐

Should the Chiefs suffer a loss on Sunday, rest assured it will not be an easy victory for their opponents. Kansas City has not been defeated by more than a touchdown at home in almost two full seasons. In fact, the Chiefs have only lost by more than one score at Arrowhead Stadium twice since 2014, discounting a meaningless Week 17 loss to the Los Angeles Chargers in the 2021 season.

Even though the Bengals have a 3-0 record against K.C. in the past two years, each of those games was won by just three points. With Mahomes confirmed to be healthy and playing, it seems like a smart move to bet on the Chiefs not losing by more than a touchdown to complete our three-leg parlay.

Parlay picks for the Conference Championships were finalized on 01/26/2026 at 8:45 p.m. ET.

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