Texans vs. Jaguars Predictions, Picks & Odds Week 3: Collins Continues Hot Start
The upcoming game at EverBank Stadium between the Jacksonville Jaguars and the Houston Texans on Sunday afternoon has sparked our top predictions. These predictions are based on the Week 3 NFL odds provided by our top sports betting apps.
The winless Houston Texans, led by rookie quarterback C.J. Stroud, take on the Jacksonville Jaguars in a clash between AFC South rivals.
In Week 2, both teams suffered defeats on their home turf. Houston was beaten by the Indianapolis Colts with a score of 31-20, while Jacksonville struggled offensively in a 17-9 loss to the Kansas City Chiefs.
Jacksonville is still the top pick to win the AFC South, with the Jaguars heavily favored over Houston in Week 3. Additionally, the Jags are one of the most popular choices for survivor pools in Week 3.
Here are our top Texans vs. Jaguars prediction and NFL picks for Week 3, along with our best bets for the NFL (odds sourced from our top NFL betting sites; confidence rating on a 1-to-5-star scale).
Texans vs. Jaguars prediction
Nico Collins Over 53.5 receiving yards (-110 via bet365) ⭐⭐⭐⭐
Initially, the Jaguars were favored by 9.5 points and appeared to be the clear choice. However, the line has since shifted in favor of the Texans due to overwhelming public support for the home team. This makes it a game to avoid. The Texans previously defeated the Jaguars 13-6 in Jacksonville last year.
After two games, it is clear that the Texans’ passing game is a strong suit. However, their run blocking is so poor that running back Dameon Pierce struggles to gain yards. The combination of a weak offensive line and constantly playing from behind leads to impressive passing numbers.
Houston wide receiver Nico Collins has been targeted 20 times in the first two weeks of the season, catching 13 passes for 226 yards with an average of 17.4 yards per reception. He has gained over 80 yards in each of his games so far and we expect his success to continue in the upcoming week.
Collins’ past performance is the main factor behind the low prop line. However, with Stroud, it’s like having a new player on the field. Stroud has had the third-highest number of passing attempts in the NFL so far this week. In another game where his team is likely to be trailing, anticipate Stroud throwing the ball frequently, especially to his preferred receiver.
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Texans vs. Jaguars best odds
bet365 (-110)
| DraftKings | FanDuel | BetMGM | Caesars | bet365 |
|---|---|---|---|---|
| Over 53.5 | Over 50.5 | Over 53.5 | Over 53.5 | Over 53.5 |
| -115 | -130 | -115 | -115 | -110 |
Out of the top five sports betting apps, four have a total of 53.5 yards listed. FanDuel, on the other hand, offers a total of 50.5 yards but at a steep price of -130, which seems excessive for just three yards.
For the best odds on a bet of 53.5, go to bet365. But also monitor FanDuel, as if their line reaches 51.5 or 52.5 at a price of -115 or higher, they will become the top choice for this wager.
Texans vs. Jaguars odds
Texans vs. Jaguars odds analysis
The Jaguars were initially favored by 9.5 points, with 77% of bets supporting them. However, the line decreased to -8.5, indicating that oddsmakers have less confidence in Jacksonville compared to the general public. It is possible that the line may return to 9 points, but it appears that key numbers are not being considered leading up to Sunday’s game.
Regarding the total, it initially opened at 44.5 and has since shifted to 44 at various major sportsbooks. Over 53% of bets are on the Over, but there hasn’t been enough momentum for significant movement. Regardless of your preference, don’t anticipate any significant changes before the game starts.
Texans vs. Jaguars game info
- When: Sunday, Sept. 24 at 1 p.m. ET
- Where: EverBank Stadium, Jacksonville, FL
- How to watch: FOX
- Weather: 92 degrees, 6% chance of precipitation, 7-mph winds
Prediction for the Texans vs. Jaguars game on Friday, September 22, 2026 at 12:12 p.m. Eastern Time.
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