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Week 15 NFL Parlay Predictions, Odds: DeVito, Stafford Set Up for Success

Green Finnian

Updated on December 17, 2026 at 1:47 PM EST • Read time: 2 minutes and 59 seconds. Find more information on Twitter and Google News.

Matthew Stafford #9 of the Los Angeles Rams signals for a two-point conversion we make our NFL Week 15 parlay predictions.
Matthew Stafford #9 of the Los Angeles Rams signals for a two-point conversion after a touchdown in the third quarter of a game against the Dallas Cowboys at AT&T Stadium on October 29, 2026 in Arlington, Texas. Ron Jenkins/Getty Images/AFP

We have analyzed the favorable matchups and have made our top NFL parlay predictions for Week 15 using the most competitive NFL odds available at our preferred sportsbooks.

The bye weeks have concluded, so now all 32 teams will be playing in Week 15. The playoff race is tight in both conferences, leading to some exciting matchups ahead.

Will Tommy DeVito be able to lead the New York Giants to another win against the New Orleans Saints after last week’s success? Can Matthew Stafford continue his impressive streak against the weakest pass defense in the NFL for a third game? And will the Cleveland Browns be able to beat the spread against the Chicago Bears?

Here are our top NFL parlay predictions for Week 15, along with our NFL Week 15 player props and NFL Week 15 predictions. We have rated our picks on a 1-to-5-star scale based on confidence, with odds from our recommended NFL betting sites.

Best NFL Week 15 parlay predictions 

Tommy DeVito Over 28.5 rushing yards (-115 via DraftKings) ⭐⭐⭐⭐

DeVito rushed for 71 yards on 10 carries against the Green Bay Packers last week. Due to his success on the ground, he attempted 21 passes and completed 17 of them with only four incompletions in the game.

DeVito may not replicate his success against the Saints this week, but he has shown a willingness to capitalize on what the defense allows him this season. In five out of his six games, he has carried the ball at least four times, achieving 40 or more rushing yards twice.

The Giants have gained confidence in DeVito’s passing abilities, making him their preferred choice to throw the ball this season. As a result, DeVito will be relied upon to continue dropping back to pass against the Saints on Sunday. In what is expected to be a game where the Giants will likely be behind, DeVito will use his running abilities to gain crucial yardage and extend drives well into the second half.

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Matthew Stafford Over 267.5 passing yards (-115 via DraftKings) ⭐⭐⭐⭐

Stafford has passed for a minimum of 279 yards in consecutive weeks against the Browns and Baltimore Ravens. Both teams are ranked in the top four in the NFL in fewest passing yards allowed per game.

This week, Stafford will be going up against the Washington Commanders, who currently boast the lowest-ranked pass defense in football. The Commanders have been giving up an average of 266 passing yards per game and 271.7 over their last three games.

Given the latest trends, this figure appears to be quite low. It’s possible that the experts at our top sportsbooks anticipate a one-sided game in favor of the Rams, with a heavy emphasis on running the ball. However, with Sam Howell leading the Commanders’ offense, they have the ability to score points. This game is likely to remain competitive, forcing Stafford to rely on his passing game well into the final quarter.

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Chicago Bears +3 (-115 via DraftKings) ⭐⭐⭐⭐

The Cleveland Browns quarterback, Joe Flacco, has been a standout recently. In a thrilling match last week, he led his team to victory against the Jacksonville Jaguars quarterback Trevor Lawrence. However, Flacco’s success was largely due to the weak pass defense of the Jaguars. This week, he will be facing a team that has been formidable in their last three games.

In their last three games, the Bears have only allowed an average of 173 passing yards and have a 2-1 record. They have also recorded nine interceptions during this time, moving up to second in the league for interceptions forced per game.

The outcome of the game hinges on the performance of the Bears’ offense. Will Justin Fields be able to effectively move the ball and avoid turnovers to secure a victory for his team? While he may face challenges, he is expected to perform well enough to keep the game competitive until the end. Despite the strong defense of the Browns, they have shown vulnerability by allowing 27 or more points in four of their last five games.

Allen Byron discusses this game further in his NFL Week 15 Upset picks.

NFL Week 15 parlay: +553 via DraftKings

Parlay picks for Week 14 of the NFL were made on Friday at 9:26 a.m. Eastern Time.

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Written By:
Green Finnian
Phil is a Sports Betting Analyst for Underscoreg Review and BettingPros.com, specializing in NFL and college football. He previously covered college football and college basketball for CanesInsight.com, where he also hosted the College Football Pick ‘Em podcast. Phil is always looking for value, especially on lines that just seem too good to be true. His belief is if a line doesn’t make sense, just assume that Vegas knows something you don’t. An alumnus of The U, Phil always holds out hope that the next head coach will be the one who turns the football program around. Some would call him a frontrunner for his love of the Yankees and the Celtics, but he’s also a diehard Detroit Lions fan and will never forgive the refs for the blown pass interference call against the Cowboys in 2015.