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Ademola Lookman of Atalanta BC celebrates after scoring a goal during the Serie A football match between Atalanta BC and US Salernitana.
Ademola Lookman of Atalanta BC celebrates after scoring a goal during the Serie A football match between Atalanta BC and US Salernitana. Photo by Mairo Cinquetti.

One of the standout matches in European soccer this week is Atalanta’s showdown with Sampdoria. Let’s take a closer look at our top soccer picks from Serie A, La Liga, Bundesliga, and other major leagues based on the most favorable odds available.

Despite being in fourth place in the Spanish league, Atletico Madrid is set to face off against their archrivals Real Madrid in the Copa del Rey quarter-finals. The winner of this highly anticipated Madrid derby will become the second major favorite to win the Spanish Cup trophy, with Barcelona already securing a spot in the semis.

Turning our attention to other matches in Europe, the Napoli vs. AS Roma showdown is sure to excite fans in Serie A, while the Bayern vs. Frankfurt and Dortmund vs. Leverkusen clashes will be the most anticipated matchups in the Bundesliga this weekend.

Below are our top picks for the upcoming European soccer weekend, with odds provided by DraftKings and FanDuel. Confidence in each pick is rated on a scale of 1 to 5 stars.

Take a look at our top soccer betting picks.

Soccer best matches and odds this week

(odds via FanDuel)

  • Spanish Cup: Real Madrid (-115) vs. Atletico Madrid (+290), Thursday, 12:30pm
  • Bundesliga: Bayern Munich (-350) vs. Eintracht Frankfurt (+700), Saturday, 12:30pm
  • Bundesliga: Leverkusen (+140) vs. Dortmund (+175), Sunday, 11:30pm
  • Serie A: Napoli (-150) vs. AS Roma (+390), Sunday, 2:45pm
  • La Liga: Real Madrid (-160) vs. Sociedad (+390), Sunday, 3pm

Soccer best bets: January 26-29

  • Total: Atalanta-Sampdoria Over 3.5 (+186 via FanDuel)
  • Spread: Freiburg -1 vs. Augsburg (+135 vs BetMGM)
  • Upset:  Salernitana Win vs. Lecce (+330 via FanDuel)
  • Parlay: RB Leipzig vs. Stuttgart: Over 3.5 Goals and Leipzig to Win (+220 via BetMGM)

Top soccer picks

Total: Atalanta-Sampdoria Over 3.5 (+186) ⭐⭐⭐⭐

Atalanta has scored three or more goals in all of their seven Serie A matches so far, showing their hunger for success. The team is currently in sixth place in the league and is determined to secure a top-four spot to qualify for the Champions League next season.

This season, Sampdoria finds themselves in a unique position, sitting second to last in the standings after 19 matches with only nine points. Their recent struggles are evident as they have failed to score in their last three games, all resulting in losses.

Atalanta is likely to take advantage of those circumstances and showcase their attacking prowess. Salernitana experienced an 8-2 defeat when they visited Bergamo two weeks ago, making national headlines. If Atalanta is in an attacking mood, Sampdoria should be wary of the potential outcome.

Spread: Freiburg -1 (+135) ⭐⭐⭐⭐

Freiburg struggled to replicate their 2022 form in recent matches against Wolfsburg (0-6) and Eintracht Frankfurt (1-1). However, it is crucial for them to demonstrate that their bid for Champions League qualification is genuine.

Augsburg may face consequences as Freiburg are favored at +135 to secure a two-goal victory, a favorable outcome given the disparity in skill between the two teams.

Upset: Salernitana to win (+330) ⭐⭐⭐

While Salernitana has struggled against Atalanta and suffered a 2-0 defeat against Serie A leaders Napoli last weekend, they have also shown moments of brilliance.

At this point in the 2021-22 season, Salernitana found themselves in a dire situation. Despite their struggles, they managed to pull off one of the most remarkable escapes in recent Italian football history. Currently, Salernitana are in 16th place on the table with 18 points, just two behind Lecce. While their recent form may not be ideal, it’s important to remember that this is the same team that defeated Lazio 3-1 at the Olimpico and held Juventus to a 2-2 draw in Turin.

Parlay:  RB Leipzig vs. Stuttgart Over 3.5 and Leipzig to win (+220) ⭐⭐⭐

Leipzig have a strong psychological advantage going into this game against Stuttgart, having won their last four home matches against them without conceding a goal. RB Leipzig are currently on a great run in the Bundesliga, sitting third in the table and just four points behind leaders Bayern Munich.

It’s difficult to envision them passing up the opportunity to secure three easy points. After a convincing 6-1 victory over Schalke, Leipzig is eager to continue their winning streak against Stuttgart and solidify their position as a strong contender against Bayern’s dominance.

Updated soccer odds and top betting picks as of 1/25/2023 at 8:35 p.m. ET.

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